Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 2/20 | 0.41 |
| ▸ | SKP1 | P63208 | 2/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2345673 | 0.86 | MAP4K4 (0.61) | MAP4K4SMARCA2SMARCA4PBRM1CKS1B | |
| SCHEMBL31703634 | 0.84 | MAPT (0.47) | MAP4K4CKS1BSKP1SKP2MAPT | |
| SCHEMBL25410640 | 0.81 | MAP4K4 (0.47) | MAP4K4SMARCA2SMARCA4PBRM1CKS1B | |
| SCHEMBL2067686 | 0.76 | MBOAT4 (0.34) | CNR2PDE10A | |
| SCHEMBL111508 | 0.76 | MAP4K4 (0.66) | MAP4K4SMARCA2SMARCA4PBRM1CKS1B | |
| SCHEMBL29545935 | 0.76 | MAP4K4 (0.66) | MAP4K4SMARCA2SMARCA4PBRM1CKS1B | |
| SCHEMBL31703650 | 0.75 | DDB1 (0.40) | MAP4K4CKS1BSKP1SKP2MAPT | |
| SCHEMBL470891 | 0.75 | MAP4K4 (0.56) | MAP4K4CKS1BSKP1SKP2MAPT | |
| SCHEMBL16434747 | 0.75 | GPR119 (0.56) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL2345124 | 0.74 | MAP4K4 (0.66) | MAP4K4HDAC2SUV39H2HDAC1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215153-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2025-10-16 | — | — | WO | disclosed |