Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24984121 | 0.89 | CMA1 (0.38) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL31005842 | 0.73 | CMA1 (0.38) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL19971631 | 0.69 | MEN1 (0.51) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL796210 | 0.69 | MEN1 (0.51) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL1010004 | 0.69 | MEN1 (0.51) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL4285281 | 0.68 | ALDH1A1 (0.42) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL6693673 | 0.68 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL11791704 | 0.65 | KDM4E (0.41) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL2865162 | 0.65 | CASP3 (0.46) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL21328320 | 0.63 | SIGMAR1 (0.46) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217319-A1 | RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS INC. (US) | 2025-10-16 | — | — | WO | disclosed |