SCHEMBL31704367

SCHEMBL31704367

C=CC(=O)N1CCC(=O)[C@@H](F)C1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.37
TEAD1 P28347 5/20 0.35
JAK3 P52333 4/20 0.34
BTK Q06187 4/20 0.34
ACHE P22303 3/20 0.34
PAX8 Q06710 1/20 0.34
CASP3 P42574 1/20 0.33
USP14 P54578 1/20 0.33
UCHL5 Q9Y5K5 1/20 0.33
TET3 O43151 1/20 0.33
KMT2A Q03164 1/20 0.33
FBXL19 Q6PCT2 1/20 0.33
CXXC5 Q7LFL8 1/20 0.33
TET1 Q8NFU7 1/20 0.33
KDM2B Q8NHM5 1/20 0.33
CXXC4 Q9H2H0 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21724773 0.78
SCHEMBL23144137 0.78
SCHEMBL731205 0.78
SCHEMBL13712734 0.72 CHRNB2 (0.40) MAPK1KMT2A
SCHEMBL20399740 0.72 DPP4 (0.42) TEAD1JAK3
SCHEMBL20849664 0.72 DPP4 (0.42) TEAD1JAK3
SCHEMBL24689072 0.72 DPP4 (0.42) TEAD1JAK3
SCHEMBL7699388 0.71 MAPK1 (0.44) MAPK1TEAD1JAK3ACHEPAX8
SCHEMBL13711179 0.70 GAA (0.41) KMT2A
SCHEMBL31561991 0.69 MAPK1 (0.37) MAPK1JAK3BTKACHEPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217336-A1 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-10-16 WO disclosed