SCHEMBL7699388

SCHEMBL7699388

C=CC(=O)N1CCC(=O)CC1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.44
TET3 O43151 4/20 0.42
KMT2A Q03164 4/20 0.42
FBXL19 Q6PCT2 4/20 0.42
CXXC5 Q7LFL8 4/20 0.42
KDM2B Q8NHM5 4/20 0.42
CXXC4 Q9H2H0 4/20 0.42
KDM2A Q9Y2K7 4/20 0.42
TET1 Q8NFU7 3/20 0.42
ACHE P22303 7/20 0.39
PAX8 Q06710 2/20 0.37
TEAD1 P28347 3/20 0.36
TEAD3 Q99594 2/20 0.36
JAK3 P52333 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31562056 0.87 MAPK1 (0.49) MAPK1TET3KMT2AFBXL19CXXC5
SCHEMBL12764449 0.83 TET3 (0.47) MAPK1TET3KMT2AFBXL19CXXC5
SCHEMBL20547259 0.83 TET3 (0.47) MAPK1TET3KMT2AFBXL19CXXC5
SCHEMBL167151 0.83 TET3 (0.47) MAPK1TET3KMT2AFBXL19CXXC5
SCHEMBL237862 0.83
SCHEMBL24160991 0.77 POLB (0.35) KMT2A
SCHEMBL31561985 0.76
Vinyl Chloride SCHEMBL11122339 0.75 TET3 (0.43) MAPK1TET3KMT2AFBXL19CXXC5
SCHEMBL149678 0.75
SCHEMBL505654 0.75 ALDH1A1 (0.48) MAPK1TET3KMT2AFBXL19CXXC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337128-B1 FOR ADHESION OF GLASS, TILES NITTO DENKO CORPORATION (JP) 2002-01-08 US claimed
US-12570655-B2 Cysteine covalent modifiers of AKT1 and uses thereof TERREMOTO BIOSCIENCES, INC. (US) 2026-03-10 US disclosed
WO-2025081045-A9 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-12-26 WO disclosed
WO-2025217330-A1 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-10-16 WO disclosed
WO-2025217336-A1 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-10-16 WO disclosed
US-20250289819-A1 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. 2025-09-18 US disclosed
WO-2025081045-A1 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-04-17 WO disclosed
US-11925651-B2 TEAD inhibitors and uses thereof Ikena Oncology, Inc. (US) 2024-03-12 US disclosed
CN-112341959-B Adhesive composition, adhesive layer, and adhesive film DIC株式会社 2024-01-05 CN disclosed
CN-112625622-B Adhesive composition, adhesive layer and adhesive film DIC株式会社 2023-10-10 CN disclosed
EP-3386992-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE Janssen Pharmaceutica, N.V. (BE) 2018-10-17 EP disclosed
WO-2018103058-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE JANSSEN PHARMACEUTICA NV (BE) 2018-06-14 WO disclosed
WO-2018103058-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE JANSSEN PHARMACEUTICA NV (BE) 2018-06-14 WO disclosed
US-20170283431-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHOD OF THEIR USE JANSSEN PHARMACEUTICA NV (BE) 2017-10-05 US disclosed
US-20170283431-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHOD OF THEIR USE JANSSEN PHARMACEUTICA NV (BE) 2017-10-05 US disclosed
US-20170283431-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHOD OF THEIR USE JANSSEN PHARMACEUTICA NV (BE) 2017-10-05 US disclosed
WO-2017100668-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE JANSSEN PHARMACEUTICA NV (BE) 2017-06-15 WO disclosed
WO-2017100668-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE JANSSEN PHARMACEUTICA NV (BE) 2017-06-15 WO disclosed
US-4567142-A CHEMICALLY STABILIZED GLUCOSE ISOMERASE NABISCO BRANDS, INC. (US) 1986-01-28 US disclosed
US-4411996-A TO FRUCTOSE, CHEMICALLY STABILIZED GLUCOSE ISOMERASE NABISCO BRANDS, INC. (US) 1983-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11925651-B2 TEAD inhibitors and uses thereof TEAD2, TEAD3, TEAD4 MAPK1 2346/4885TET3 2248/4885KMT2A 2717/4885
US-12570655-B2 Cysteine covalent modifiers of AKT1 and uses thereof AKT1, AKT2, AKT3 MAPK1 178/4885TET3 3131/4885KMT2A 1229/4885
US-20170283431-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHOD OF THEIR USE ABL1, BTK, MYLK2 MAPK1 385/4885TET3 3156/4885KMT2A 2626/4885
US-20250289819-A1 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF AKT1, AKT2, AKT3 MAPK1 165/4885TET3 3108/4885KMT2A 932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.