Sugi Predict

Sugi Predict / Compounds / SCHEMBL31704900

SCHEMBL31704900

SCHEMBL31704900

COC(=O)c1cc(C)cc(C2=CCCN(C(=O)OC(C)(C)C)C2)c1.COC(=O)c1cc(OS(=O)(=O)C(F)(F)F)cc(C2=CCCN(C(=O)O)C2)c1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 2/20 0.34
▸ WDR5 P61964 2/20 0.34
▸ STS P08842 2/20 0.32
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ ESR2 Q92731 1/20 0.31
▸ RORC P51449 1/20 0.31
▸ EPHX2 P34913 2/20 0.31
▸ MMP13 P45452 1/20 0.31
▸ NR1H3 Q13133 1/20 0.31
▸ PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31706274 0.93 NR1H2 (0.38) NR1H2WDR5STSESR2RORC
SCHEMBL31704801 0.86 NR1H2 (0.43) NR1H2WDR5MEN1KMT2AESR2
SCHEMBL31705120 0.81 NAMPT (0.44) —
SCHEMBL31706443 0.76 ESR2 (0.45) NR1H2WDR5KMT2AESR2PKM
SCHEMBL31704979 0.76 ESR2 (0.45) NR1H2WDR5KMT2AESR2PKM
SCHEMBL31706330 0.75 CDK7 (0.41) —
SCHEMBL31704684 0.73 NR1H2 (0.40) NR1H2WDR5ESR2RORCPKM
SCHEMBL31705023 0.73 NR1H2 (0.40) NR1H2WDR5ESR2RORCPKM
SCHEMBL31649256 0.72 NR1H2 (0.49) NR1H2MEN1KMT2AESR2PKM
SCHEMBL15649776 0.72 ALDH1A1 (0.43) NR1H2STSESR2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025215110-A1 NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS LES LABORATOIRES SERVIER (FR) 2025-10-16 — — WO disclosed
Send feedback