Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 11/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31705462 | 1.00 | MAOA (0.38) | MAOAACHENAMPTJAK1JAK2 | |
| SCHEMBL31705868 | 0.87 | ALDH1A1 (0.38) | NAMPTJAK1JAK2TYK2 | |
| Lithium Ion SCHEMBL31705930 | 0.85 | NAMPT (0.36) | NAMPTJAK1JAK2TYK2GPR119 | |
| SCHEMBL31705068 | 0.81 | NAMPT (0.40) | NAMPTJAK1JAK2TYK2CCNT1 | |
| SCHEMBL31706013 | 0.81 | NAMPT (0.40) | NAMPTJAK1JAK2TYK2CCNT1 | |
| SCHEMBL31706494 | 0.81 | NAMPT (0.41) | NAMPTCCNT1CDK9HRH3 | |
| SCHEMBL31706303 | 0.81 | NAMPT (0.41) | NAMPTCCNT1CDK9HRH3 | |
| SCHEMBL31705195 | 0.80 | NAMPT (0.41) | NAMPTJAK1JAK2TYK2CCNT1 | |
| SCHEMBL31704732 | 0.79 | CCNT1 (0.44) | NAMPTCCNT1CDK9 | |
| SCHEMBL31705807 | 0.79 | GPR119 (0.56) | NAMPTJAK1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |