Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31705292 | 1.00 | KMO (0.41) | KMOPOLBALDH1A1HPGDBLM | |
| SCHEMBL21200382 | 0.91 | KMO (0.47) | KMOPOLBALDH1A1HPGDBLM | |
| SCHEMBL31706056 | 0.78 | LMNA (0.51) | ALDH1A1RORCALOX15PIK3CAKDM4E | |
| SCHEMBL31705056 | 0.75 | KMO (0.71) | KMO | |
| SCHEMBL31704503 | 0.74 | KDM4E (0.41) | KMOALDH1A1KDM5BMAPTSMN1; SMN2 | |
| SCHEMBL31514264 | 0.74 | HCAR2 (0.47) | KMOPOLBALDH1A1KDM5BMAPT | |
| SCHEMBL13769311 | 0.74 | HCAR2 (0.43) | ALDH1A1HPGDHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL719425 | 0.74 | HCAR2 (0.47) | KMOPOLBALDH1A1KDM5BMAPT | |
| SCHEMBL25136442 | 0.73 | GSK3B (0.39) | KMOPOLBALDH1A1HPGDBLM | |
| SCHEMBL31704485 | 0.73 | HCAR2 (0.36) | KMOHCAR2PIK3CDPIK3CAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |