Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21200220 | 0.90 | TDP1 (0.58) | LMNATDP1RBP4GPR35ALOX15 | |
| SCHEMBL31706025 | 0.88 | ALDH1A1 (0.43) | LMNATDP1RBP4ALDH1A1KDM4E | |
| SCHEMBL31705179 | 0.88 | ALDH1A1 (0.43) | LMNATDP1RBP4ALDH1A1KDM4E | |
| SCHEMBL31704988 | 0.78 | KMO (0.41) | ALOX15ALDH1A1KDM4ERORCPIK3CA | |
| SCHEMBL31705292 | 0.78 | KMO (0.41) | ALOX15ALDH1A1KDM4ERORCPIK3CA | |
| SCHEMBL21200027 | 0.77 | ALDH1A1 (0.49) | LMNATDP1RBP4ALDH1A1KDM4E | |
| SCHEMBL3113677 | 0.72 | LMNA (0.51) | LMNATDP1RBP4ALDH1A1KDM4E | |
| SCHEMBL31706429 | 0.71 | KDM4E (0.40) | KDM4ERORCRAF1GRM5 | |
| SCHEMBL6341486 | 0.71 | PDE10A (0.45) | LMNAALDH1A1KDM4EHTR1ACYP1A2 | |
| SCHEMBL31704503 | 0.71 | KDM4E (0.41) | LMNATDP1RBP4ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |