Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DDO | Q99489 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29810615 | 0.88 | HCAR2 (0.50) | CYP11B2HCAR2KDM4EALDH1A1MEN1 | |
| SCHEMBL17067759 | 0.88 | HCAR2 (0.50) | CYP11B2HCAR2KDM4EALDH1A1MEN1 | |
| SCHEMBL30678406 | 0.86 | CYP11B2 (0.51) | CYP11B2CYP11B1MAPK1 | |
| SCHEMBL30281197 | 0.85 | KMO (0.51) | CYP11B2HCAR2KDM4EALDH1A1MEN1 | |
| Lithium Ion SCHEMBL31706306 | 0.84 | CYP11B2 (0.42) | CYP11B2CYP11B1SERPINE1MAPK1 | |
| Lithium Ion SCHEMBL31706663 | 0.84 | CYP11B2 (0.42) | CYP11B2CYP11B1SERPINE1MAPK1 | |
| SCHEMBL31705854 | 0.82 | ATM (0.50) | CYP11B2CYP11B1ALDH1A1NPC1RAB9A | |
| SCHEMBL31704913 | 0.82 | ATM (0.50) | CYP11B2CYP11B1ALDH1A1NPC1RAB9A | |
| SCHEMBL13406401 | 0.81 | P2RY14 (0.47) | CYP11B2HCAR2KDM4EALDH1A1MEN1 | |
| SCHEMBL31704975 | 0.79 | HCAR2 (0.40) | HCAR2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |