Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | ACACA | Q13085 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31705731 | 0.85 | HTR2B (0.42) | CHEK1PDCD1CD274TP53MAPT | |
| SCHEMBL15264604 | 0.84 | KDM4E (0.40) | ALDH1A1 | |
| Lithium Ion SCHEMBL31706490 | 0.82 | HTR2B (0.38) | CHEK1PDCD1CD274TP53MAPT | |
| Lithium Ion SCHEMBL31704920 | 0.82 | HTR2B (0.38) | CHEK1PDCD1CD274TP53MAPT | |
| SCHEMBL31705767 | 0.82 | TRPV3 (0.48) | MAPTALDH1A1 | |
| SCHEMBL31705275 | 0.81 | CKS1B (0.48) | TP53MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31705550 | 0.81 | CKS1B (0.48) | TP53MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31704762 | 0.78 | TLR9 (0.42) | TLR9TLR8 | |
| SCHEMBL31705266 | 0.77 | TLR8 (0.48) | MEN1KMT2APDE2ACFTRALDH1A1 | |
| SCHEMBL31706011 | 0.74 | KMO (0.44) | MEN1KMT2APDE2ASMN1; SMN2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |