Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706018 | 0.86 | RBP4 (0.40) | RETMAPTALDH1A1MAPK1 | |
| Lithium Ion SCHEMBL31705320 | 0.84 | CASP1 (0.33) | RETACVR1ALDH1A1 | |
| Lithium Ion SCHEMBL31706297 | 0.84 | CASP1 (0.33) | RETACVR1ALDH1A1 | |
| SCHEMBL31706352 | 0.81 | HRH3 (0.38) | KDM4EHRH3MAPTALDH1A1NPC1 | |
| SCHEMBL24993525 | 0.81 | DRD2 (0.40) | KDM4EHRH3ALDH1A1 | |
| SCHEMBL31705338 | 0.79 | PIK3CA (0.44) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL24993524 | 0.79 | PIK3CA (0.44) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL31014743 | 0.77 | NPC1 (0.40) | KDM4EHRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31705614 | 0.77 | ATM (0.41) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31706184 | 0.76 | CRBN (0.45) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |