Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.37 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.37 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL31705364 | 0.88 | CHRNB2 (0.37) | CHRNB2CHRNA4PLOD2PLOD3PLOD1 | |
| Lithium Ion SCHEMBL31705412 | 0.88 | CHRNB2 (0.37) | CHRNB2CHRNA4PLOD2PLOD3PLOD1 | |
| SCHEMBL31705614 | 0.86 | ATM (0.41) | PLOD2PLOD3PLOD1BRAFNPC1 | |
| SCHEMBL31704987 | 0.81 | BRAF (0.40) | CHRNB2CHRNA4CHEK1PLOD2PLOD3 | |
| SCHEMBL29420013 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA4CHEK1KMOCHRNB4 | |
| SCHEMBL20187819 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA4CHEK1KMOCHRNB4 | |
| SCHEMBL686827 | 0.77 | KMO (0.60) | CHRNB2CHRNA4CHEK1PLOD2PLOD3 | |
| SCHEMBL31706768 | 0.77 | KMO (0.60) | CHRNB2CHRNA4CHEK1PLOD2PLOD3 | |
| SCHEMBL23610380 | 0.76 | CHRNB2 (0.55) | CHRNB2CHRNA4CHEK1KMONPC1 | |
| SCHEMBL29420017 | 0.76 | CHRNB2 (0.55) | CHRNB2CHRNA4CHEK1KMONPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |