Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29420013 | 0.85 | CHRNB2 (0.51) | CHEK1HCAR2CHRNB2CHRNA4KDM4E | |
| SCHEMBL20187819 | 0.85 | CHRNB2 (0.51) | CHEK1HCAR2CHRNB2CHRNA4KDM4E | |
| Lithium Ion SCHEMBL31705050 | 0.85 | CHRNB2 (0.42) | CHEK1CHRNB2CHRNA4ALDH1A1LMNA | |
| Lithium Ion SCHEMBL31706241 | 0.85 | CHRNB2 (0.42) | CHEK1CHRNB2CHRNA4ALDH1A1LMNA | |
| SCHEMBL31705857 | 0.84 | ATM (0.49) | CHRNB2CHRNA4ALDH1A1KMT2ACHRNB4 | |
| SCHEMBL31706868 | 0.84 | ATM (0.49) | CHRNB2CHRNA4ALDH1A1KMT2ACHRNB4 | |
| SCHEMBL5593185 | 0.82 | ALDH1A1 (0.57) | CHEK1HCAR2CHRNB2CHRNA4KDM4E | |
| SCHEMBL23610380 | 0.81 | CHRNB2 (0.55) | CHEK1HCAR2CHRNB2CHRNA4KDM4E | |
| SCHEMBL29420017 | 0.81 | CHRNB2 (0.55) | CHEK1HCAR2CHRNB2CHRNA4KDM4E | |
| SCHEMBL3941724 | 0.81 | KDM4E (0.56) | CHEK1HCAR2CHRNB2CHRNA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |