Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31704665 | 0.90 | TBK1 (0.38) | OPRM1TLR9TLR8TLR7ALDH1A1 | |
| Lithium Ion SCHEMBL31704679 | 0.84 | OPRM1 (0.34) | OPRM1GSK3BDYRK1AHDAC2 | |
| Lithium Ion SCHEMBL31704957 | 0.84 | OPRM1 (0.34) | OPRM1GSK3BDYRK1AHDAC2 | |
| SCHEMBL31705531 | 0.83 | CCNT1 (0.38) | OPRM1ALDH1A1CCNT1CDK9 | |
| SCHEMBL31706475 | 0.76 | TLR9 (0.47) | OPRM1TLR9TLR8TLR7 | |
| SCHEMBL31704952 | 0.75 | NR1H2 (0.45) | ARCCNT1CDK9 | |
| SCHEMBL31705108 | 0.74 | TLR9 (0.42) | OPRM1TLR9TLR8TLR7 | |
| Lithium Ion SCHEMBL31705265 | 0.74 | TBK1 (0.35) | OPRM1ALDH1A1HDAC2 | |
| Lithium Ion SCHEMBL31704782 | 0.74 | TBK1 (0.35) | OPRM1ALDH1A1HDAC2 | |
| SCHEMBL31706532 | 0.73 | MKNK1 (0.48) | AXLFLT3TYRO3MERTKWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |