Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.48 |
| ▸ | EIF4E | P06730 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 3/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706350 | 1.00 | MKNK1 (0.48) | MKNK1MKNK2EIF4ELRRK2BRD4 | |
| SCHEMBL31704583 | 0.85 | KIT (0.46) | MKNK1MKNK2EIF4ELRRK2BRD4 | |
| Lithium Ion SCHEMBL31704516 | 0.83 | KIT (0.45) | MKNK1MKNK2EIF4ELRRK2BRD4 | |
| Lithium Ion SCHEMBL31705351 | 0.83 | KIT (0.45) | MKNK1MKNK2EIF4ELRRK2BRD4 | |
| SCHEMBL23012096 | 0.77 | GRK5 (0.41) | MKNK1MKNK2EIF4EBRD4PIM1 | |
| SCHEMBL31165961 | 0.77 | GRK5 (0.41) | MKNK1MKNK2EIF4EBRD4PIM1 | |
| SCHEMBL24296549 | 0.77 | MAP3K5 (0.47) | MAP3K5WNT1GSK3BDYRK1AKCNH2 | |
| SCHEMBL30800091 | 0.75 | ALDH1A1 (0.54) | MAPK1 | |
| SCHEMBL24035877 | 0.74 | ROCK1 (0.44) | MKNK1MKNK2EIF4ELRRK2BRD4 | |
| SCHEMBL31704964 | 0.74 | MKNK1 (0.45) | MKNK1MKNK2BRD4TTKWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |