Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326306 | 0.98 | LTA4H (0.53) | LTA4HCYSLTR2CYSLTR1MAPTBRD4 | |
| SCHEMBL7045164 | 0.94 | BRD4 (0.54) | LTA4HCYSLTR2CYSLTR1MAPTBRD4 | |
| SCHEMBL14570538 | 0.88 | MEN1 (0.59) | LTA4HCYSLTR2CYSLTR1MAPTBRD4 | |
| SCHEMBL17266636 | 0.87 | MAPT (0.52) | LTA4HCYSLTR2CYSLTR1MAPTBRD4 | |
| SCHEMBL19474670 | 0.86 | LTA4H (0.53) | LTA4HCYSLTR2CYSLTR1MAPTBRD4 | |
| SCHEMBL7747836 | 0.86 | NR5A1 (0.60) | LTA4HCYSLTR2CYSLTR1MAPTBRD4 | |
| SCHEMBL15104736 | 0.86 | NR5A1 (0.60) | LTA4HCYSLTR2CYSLTR1MAPTBRD4 | |
| SCHEMBL16264850 | 0.86 | MEN1 (0.60) | LTA4HCYSLTR2CYSLTR1MAPTBRD4 | |
| SCHEMBL765455 | 0.85 | LTA4H (0.58) | LTA4HCYSLTR2CYSLTR1MAPTBRD4 | |
| SCHEMBL17265678 | 0.85 | LTA4H (0.52) | LTA4HCYSLTR2CYSLTR1MAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642373-B2 | Forming for example [18F]-dopamine or [18F]-uracil via reaction of iodonium salt precursor, where use of free radical scavenger improves yield of aryl fluoride | GE HEALTHCARE LIMITED (GB) | 2010-01-05 | — | — | US | disclosed |
| US-7642373-B2 | Forming for example [18F]-dopamine or [18F]-uracil via reaction of iodonium salt precursor, where use of free radical scavenger improves yield of aryl fluoride | GE HEALTHCARE LIMITED (GB) | 2010-01-05 | — | — | US | disclosed |
| EP-1697279-B1 | RADICAL TRAP IN FLUORIDATION OF IODINIUM SALT | GE HEALTHCARE LTD (GB) | 2008-09-24 | — | — | EP | disclosed |
| US-20060292060-A1 | Forming for example [18F]-dopamine or [18F]-uracil via reaction of iodonium salt precursor, where use of free radical scavenger improves yield of aryl fluoride | GE HEALTHCARE LIMITED (GB) | 2006-12-28 | — | — | US | disclosed |
| EP-1697279-A1 | RADICAL TRAP IN FLUORIDATION OF IODINIUM SALT | GE Healthcare Limited (GB) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061415-A1 | RADICAL TRAP IN FLUORIDATION OF IODONIUM SALT | GE HEALTHCARE LIMITED (GB) | 2005-07-07 | — | — | WO | disclosed |