Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3170654 | 0.98 | LTA4H (0.52) | LTA4HCYSLTR2CYSLTR1BRD4MAPT | |
| SCHEMBL7045164 | 0.95 | BRD4 (0.54) | LTA4HCYSLTR2CYSLTR1BRD4MAPT | |
| SCHEMBL17266636 | 0.88 | MAPT (0.52) | LTA4HCYSLTR2CYSLTR1BRD4MAPT | |
| SCHEMBL16264850 | 0.87 | MEN1 (0.60) | LTA4HCYSLTR2CYSLTR1BRD4MAPT | |
| SCHEMBL8620576 | 0.86 | LTA4H (0.54) | LTA4HCYSLTR2CYSLTR1BRD4MAPT | |
| SCHEMBL14570538 | 0.86 | MEN1 (0.59) | LTA4HCYSLTR2CYSLTR1BRD4MAPT | |
| SCHEMBL19474670 | 0.84 | LTA4H (0.53) | LTA4HCYSLTR2CYSLTR1BRD4MAPT | |
| SCHEMBL5493279 | 0.84 | LTA4H (0.53) | LTA4HCYSLTR2CYSLTR1BRD4MAPT | |
| SCHEMBL7747836 | 0.84 | NR5A1 (0.60) | LTA4HCYSLTR2CYSLTR1BRD4MAPT | |
| SCHEMBL15104736 | 0.84 | NR5A1 (0.60) | LTA4HCYSLTR2CYSLTR1BRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063169-A1 | HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-07-29 | — | — | WO | disclosed |