Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 7/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL31705638 | 0.88 | DGAT2 (0.35) | DGAT2HTR2BNAMPTTNKSTNKS2 | |
| Lithium Ion SCHEMBL31706463 | 0.88 | DGAT2 (0.35) | DGAT2HTR2BNAMPTTNKSTNKS2 | |
| SCHEMBL31705105 | 0.85 | CHRM4 (0.37) | DGAT2NAMPTALDH1A1POLBCHEK1 | |
| SCHEMBL29516981 | 0.79 | KMO (0.41) | ALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL31706074 | 0.78 | CNR2 (0.41) | DGAT2ALDH1A1POLBHPGDBLM | |
| SCHEMBL31706914 | 0.76 | CNR2 (0.36) | DGAT2HTR2BNAMPTTNKSTNKS2 | |
| SCHEMBL31705035 | 0.76 | MAPT (0.39) | NAMPTALDH1A1POLBHPGDBLM | |
| SCHEMBL31704689 | 0.75 | SMYD3 (0.52) | ALDH1A1SMYD3POLB | |
| SCHEMBL31706109 | 0.74 | NAMPT (0.40) | HTR2BNAMPTALDH1A1POLB | |
| SCHEMBL31705580 | 0.74 | SCD (0.37) | NAMPTTNKSTNKS2SMYD3CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |