SCHEMBL31707366

SCHEMBL31707366

COc1ccc(-c2cc(-c3ccccc3)c3ccccc3n2)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACA Q13085 2/20 1.00
DHODH Q02127 2/20 0.64
HPGD P15428 4/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
LMNA P02545 2/20 0.63
KDM4E B2RXH2 6/20 0.62
ALDH1A1 P00352 5/20 0.62
KMT2A Q03164 4/20 0.62
MEN1 O00255 3/20 0.62
HTT P42858 2/20 0.62
NPC1 O15118 2/20 0.62
RAB9A P51151 1/20 0.62
USP2 O75604 1/20 0.62
TSHR P16473 1/20 0.62
MAPK1 P28482 1/20 0.62
ATM Q13315 1/20 0.62
HSD17B10 Q99714 1/20 0.62
L3MBTL1 Q9Y468 2/20 0.61
MAPT P10636 3/20 0.57
AGTR1 P30556 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16294371 1.00 ACACA (1.00) ACACADHODHHPGDSMN1; SMN2LMNA
SCHEMBL21290389 0.87 ACACA (0.78) ACACADHODHHPGDSMN1; SMN2LMNA
SCHEMBL5999877 0.85 ACACA (0.73) ACACADHODHHPGDSMN1; SMN2LMNA
SCHEMBL21290148 0.83 ACACA (0.70) ACACADHODHHPGDSMN1; SMN2LMNA
SCHEMBL29726805 0.82 ACACA (1.00) ACACAHPGDSMN1; SMN2LMNAKDM4E
SCHEMBL25522200 0.82 ACACA (1.00) ACACAHPGDSMN1; SMN2LMNAKDM4E
SCHEMBL16295684 0.82 ACACA (1.00) ACACAHPGDSMN1; SMN2LMNAKDM4E
SCHEMBL42477 0.81 DHODH (0.81) ACACADHODHHPGDSMN1; SMN2LMNA
SCHEMBL29788461 0.81 DHODH (0.81) ACACADHODHHPGDSMN1; SMN2LMNA
SCHEMBL4594838 0.81 ACACA (0.75) ACACADHODHHPGDSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109673-A1 ACETYL-COA CARBOXYLASE MODULATORS MONSANTO TECHNOLOGY LLC (US) 2026-04-23 US disclosed
US-12448355-B2 Acetyl-CoA carboxylase modulators MONSANTO TECHNOLOGY LLC (US) 2025-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12448355-B2 Acetyl-CoA carboxylase modulators ACACA, ACACB, ACAT2 ACACA 1/4885DHODH 879/4885HPGD 800/4885
US-20260109673-A1 ACETYL-COA CARBOXYLASE MODULATORS ACACA, ACACB, HACL2 ACACA 1/4885DHODH 1592/4885HPGD 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.