SCHEMBL3780946

SCHEMBL3780946

C=C(C)C(=O)Oc1ccc(Cl)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.50
KMT2A Q03164 2/20 0.46
ATM Q13315 1/20 0.46
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.42
KMO O15229 2/20 0.41
CHRNA3 P32297 1/20 0.41
HSP90AA1 P07900 1/20 0.41
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
ABCB11 O95342 1/20 0.38
TSHR P16473 2/20 0.37
MRGPRX4 Q96LA9 1/20 0.37
MAPT P10636 1/20 0.37
FFAR1 O14842 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507367 0.85 KDM4E (0.44) ATMKDM4EALDH1A1LMNAKMO
SCHEMBL8835865 0.83 ELANE (0.45) ELANEKMT2AATMKDM4EALDH1A1
SCHEMBL11312335 0.83 ELANE (0.45) ELANEKMT2AATMALDH1A1LMNA
SCHEMBL23520512 0.82 ELANE (0.48) ELANEKMT2AATMKDM4E
SCHEMBL11312257 0.81 ELANE (0.45) ELANEKMT2AATMALDH1A1LMNA
SCHEMBL11124119 0.81 KMO (0.44) KDM4EALDH1A1LMNAKMOCHRNA3
SCHEMBL473532 0.81 LMNA (0.52) ELANEKMT2AKDM4EALDH1A1LMNA
SCHEMBL803231 0.81 ELANE (0.56) ELANEKMT2AATMKDM4EALDH1A1
SCHEMBL56436 0.80 ELANE (0.69) ELANEKMT2AATMKDM4EALDH1A1
SCHEMBL452065 0.79 ELANE (0.59) ELANEKMT2AATMLMNAPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1917236-B1 CHROMOPHORIC POLYMER MEMPILE INC (US) 2010-08-18 EP claimed
US-20080197322-A1 ADDITIVES AND COMONOMERS FOR THE ENHANCEMENT OF POLYMER PROPERTIES MEMPILE INC. (US) 2008-08-21 US claimed
EP-1917236-A1 CHROMOPHORIC POLYMER Mempile Inc. (US) 2008-05-07 EP claimed
WO-2007010519-A1 CHROMOPHORIC POLYMER MEMPILE INC. (US) 2007-01-25 WO claimed
EP-1917236-B1 CHROMOPHORIC POLYMER MEMPILE INC (US) 2010-08-18 EP disclosed
EP-1917236-B1 CHROMOPHORIC POLYMER MEMPILE INC (US) 2010-08-18 EP disclosed
US-20080197322-A1 ADDITIVES AND COMONOMERS FOR THE ENHANCEMENT OF POLYMER PROPERTIES MEMPILE INC. (US) 2008-08-21 US disclosed
US-20080197322-A1 ADDITIVES AND COMONOMERS FOR THE ENHANCEMENT OF POLYMER PROPERTIES MEMPILE INC. (US) 2008-08-21 US disclosed
US-20080197322-A1 ADDITIVES AND COMONOMERS FOR THE ENHANCEMENT OF POLYMER PROPERTIES MEMPILE INC. (US) 2008-08-21 US disclosed
EP-1917236-A1 CHROMOPHORIC POLYMER Mempile Inc. (US) 2008-05-07 EP disclosed
WO-2007010519-A1 CHROMOPHORIC POLYMER MEMPILE INC. (US) 2007-01-25 WO disclosed
WO-2007010519-A1 CHROMOPHORIC POLYMER MEMPILE INC. (US) 2007-01-25 WO disclosed
EP-0008787-B1 BINDER FOR AN ELECTRON BEAM POSITIVE RESISTING LACQUER BAYER AG (DE) 1981-08-12 EP disclosed
US-4262082-A Positive electron beam resists BAYER AKTIENGESELLSCHAFT (DE) 1981-04-14 US disclosed
EP-0008787-A1 Binder for an electron beam positive resisting lacquer BAYER AG (DE) 1980-03-19 EP disclosed