Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3182451 | 0.94 | ALDH1A1 (0.43) | ALDH1A1KMT2AGAALTA4HHTT | |
| SCHEMBL3177192 | 0.91 | KMT2A (0.46) | ALDH1A1KMT2AGAALTA4HHTT | |
| SCHEMBL3170543 | 0.89 | ALDH1A1 (0.46) | ALDH1A1KMT2AGAAHTTATM | |
| SCHEMBL3161531 | 0.87 | LTA4H (0.44) | ALDH1A1KMT2AGAALTA4HMEN1 | |
| SCHEMBL3171502 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KMT2AGAAHTTATM | |
| SCHEMBL3161693 | 0.84 | FFAR1 (0.47) | ALDH1A1KMT2AGAAHTTATM | |
| SCHEMBL3170525 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KMT2AGAAHTTKLK7 | |
| SCHEMBL3175077 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KMT2AGAAHTTATM | |
| SCHEMBL3174637 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KMT2AGAAHTTKLK7 | |
| SCHEMBL3161214 | 0.83 | ALDH1A1 (0.47) | ALDH1A1GAAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645607-B2 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-12 | — | — | US | disclosed |
| EP-1705252-B1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20060216806-A1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-09-28 | — | — | US | disclosed |
| EP-1705252-A1 | Method for producing optically active N-protected-propargylglycine | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |