Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 4/20 | 0.35 |
| ▸ | GABRD | O14764 | 4/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.35 |
| ▸ | GABRE | P78334 | 4/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31708151 | 0.74 | IGF1R (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30712084 | 0.74 | IGF1R (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13325448 | 0.70 | CES2 (0.38) | HTR1A | |
| SCHEMBL31708141 | 0.68 | NR4A2 (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31708047 | 0.67 | GABRP (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25423716 | 0.67 | CES2 (0.38) | HTR1A | |
| SCHEMBL31708139 | 0.67 | HTR1A (0.66) | HTR1AMPO | |
| SCHEMBL25748764 | 0.67 | HTR1A (0.39) | HTR1A | |
| SCHEMBL17303510 | 0.66 | GAA (0.36) | — | |
| SCHEMBL29953426 | 0.66 | HTR1A (0.47) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635492-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |