Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31708882 | 0.93 | SIGMAR1 (0.57) | SIGMAR1KDM4EALOX15ALDH1A1CHRM2 | |
| SCHEMBL31708704 | 0.90 | ALDH1A1 (0.52) | SIGMAR1KDM4EALOX15ALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL27148010 | 0.89 | ALDH1A1 (0.51) | SIGMAR1KDM4EALOX15ALDH1A1CHRM2 | |
| SCHEMBL31708992 | 0.89 | SIGMAR1 (0.50) | SIGMAR1KDM4EALOX15ALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL27148014 | 0.89 | ALDH1A1 (0.51) | SIGMAR1KDM4EALOX15ALDH1A1CHRM2 | |
| SCHEMBL27154412 | 0.89 | KDM4E (0.56) | SIGMAR1KDM4EALOX15ALDH1A1CHRM3 | |
| SCHEMBL27154411 | 0.89 | KDM4E (0.56) | SIGMAR1KDM4EALOX15ALDH1A1CHRM3 | |
| SCHEMBL31708856 | 0.89 | KDM4E (0.56) | SIGMAR1KDM4EALOX15ALDH1A1CHRM3 | |
| SCHEMBL31709169 | 0.88 | SIGMAR1 (0.48) | SIGMAR1KDM4EALOX15ALDH1A1POLB | |
| SCHEMBL31708922 | 0.87 | KDM4E (0.45) | SIGMAR1KDM4EALOX15ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | ABCB11, ABCC1, SLC11A2 | SIGMAR1 197/4885KDM4E 2774/4885ALOX15 1853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.