Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28413841 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ALOX15ITGB3ITGA2BITGAV | |
| SCHEMBL28413840 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ALOX15ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL29635979 | 0.99 | ALDH1A1 (0.49) | ALDH1A1ALOX15ITGB3ITGA2BITGAV | |
| SCHEMBL22552570 | 0.90 | ITGB3 (0.53) | ALDH1A1ITGB3ITGA2BITGAVTSHR | |
| SCHEMBL21062759 | 0.90 | ITGB3 (0.53) | ALDH1A1ITGB3ITGA2BITGAVTSHR | |
| SCHEMBL21062760 | 0.90 | ITGB3 (0.53) | ALDH1A1ITGB3ITGA2BITGAVTSHR | |
| Hydrochloric Acid SCHEMBL22552738 | 0.89 | ITGB3 (0.53) | ALDH1A1ITGB3ITGA2BITGAVTSHR | |
| Hydrochloric Acid SCHEMBL27147667 | 0.89 | ITGB3 (0.53) | ALDH1A1ITGB3ITGA2BITGAVTSHR | |
| Hydrochloric Acid SCHEMBL22552736 | 0.89 | ITGB3 (0.53) | ALDH1A1ITGB3ITGA2BITGAVTSHR | |
| SCHEMBL15898117 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ALOX15TSHRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | ABCB11, ABCC1, SLC11A2 | ALDH1A1 774/4885ALOX15 1853/4885ITGB3 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.