Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27743535 | 0.84 | HCAR2 (0.51) | HCAR2ESR1ESR2TDP1NPC1 | |
| SCHEMBL28893772 | 0.84 | HCAR2 (0.51) | HCAR2ESR1ESR2TDP1NPC1 | |
| SCHEMBL585944 | 0.84 | HCAR2 (0.51) | HCAR2ESR1ESR2TDP1NPC1 | |
| SCHEMBL19105213 | 0.84 | HCAR2 (0.51) | HCAR2ESR1ESR2TDP1NPC1 | |
| SCHEMBL8954716 | 0.83 | HCAR2 (0.50) | HCAR2ESR1ESR2TDP1NPC1 | |
| SCHEMBL872788 | 0.83 | HCAR2 (0.50) | HCAR2ESR1ESR2TDP1NPC1 | |
| SCHEMBL30879570 | 0.83 | HCAR2 (0.50) | HCAR2ESR1ESR2TDP1NPC1 | |
| SCHEMBL18656681 | 0.82 | HCAR2 (0.53) | HCAR2ESR1ESR2TDP1NPC1 | |
| SCHEMBL5768186 | 0.82 | ALDH1A1 (0.58) | HCAR2TDP1NPC1RAB9AL3MBTL1 | |
| SCHEMBL10491290 | 0.82 | HCAR2 (0.53) | HCAR2ESR1ESR2TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408107-B1 | Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene | DAISO CO LTD (JP) | 2010-03-24 | — | — | EP | disclosed |
| US-7335502-B2 | Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene | DAISO CO., LTD. (JP) | 2008-02-26 | — | — | US | disclosed |
| US-20060257988-A1 | Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene | NAKAGAWA ATSUSHI | 2006-11-16 | — | — | US | disclosed |
| US-7112428-B2 | Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene | DAISO CO., LTD. (JP) | 2006-09-26 | — | — | US | disclosed |
| US-20040132154-A1 | Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene | OSAKA SODA CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
| EP-1408107-A2 | Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene | DAISO CO., LTD. (JP) | 2004-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132154-A1 | Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene | HDHD5, PHGDH, EI24 | HCAR2 729/4885ESR1 635/4885ESR2 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.