EI24

Etoposide-induced protein 2.4 homolog · O14681 · EI24 on Sugi Atlas →

11 patent compounds predicted against EI24, 8 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL21943538 SCHEMBL21943538 0.59 1/20
SCHEMBL21943762 SCHEMBL21943762 0.57 1/20
SCHEMBL21944043 SCHEMBL21944043 0.55 1/20
SCHEMBL21943004 SCHEMBL21943004 0.55 1/20
SCHEMBL21942995 SCHEMBL21942995 0.53 1/20
SCHEMBL21943411 SCHEMBL21943411 0.53 1/20
SCHEMBL21943540 SCHEMBL21943540 0.49 1/20
SCHEMBL29911712 SCHEMBL29911712 0.40 1/20

Clinical trials — most relevant to EI24 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Does Aldosterone Cause Hypertension by a Non-Renal Mechanism? PHASE4UNKNOWN
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Safety and Efficacy Study of INGN 241 Gene Therapy in Patients With In Transit Melanoma PHASE2UNKNOWN
Pharmacogenomic & Phase II Study of Gemcitabine and Pemetrexed in Non-Small-Cell Lung Cancer. PHASE2COMPLETED
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma PHASE2COMPLETED
Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia PHASE1/PHASE2UNKNOWN
Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity PHASE2RECRUITING
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors PHASE1COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
LBH589 Oral in Combination With Carboplatin and Paclitaxel in Advanced Solid Tumors PHASE1UNKNOWN
Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations EARLY_PHASE1COMPLETED
A Study of the Interaction Between Tumor Susceptibility Gene Glycine N-methyltransferase (GNMT) and Lung Cancer nanUNKNOWN
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Study of Tissue Samples in Predicting How Well Chemotherapy and Radiation Therapy Will Kill Cancer Cells in Patients With Squamous Cell Carcinoma of the Esophagus nanUNKNOWN
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Biomarker in Tissue Samples From Patients With Ewing Sarcoma nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Developing Genetic Education for Smoking Cessation nanCOMPLETED
DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease nanCOMPLETED
Evaluation of Vasopressin in the Vessels of Ovarian Neoplasms nanCOMPLETED
A Pilot Study of Parenteral Testosterone and Oral Etoposide as Therapy for Men With Castration Resistant Prostate Cancer nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions nanCOMPLETED
Genetic Investigation of Solid Tumors Cohort nanCOMPLETED
Transcriptional Responses as an Indicator of Individualised Responses to Radiation Effects (RTGene 2) nanACTIVE_NOT_RECRUITING
Biomarkers in Patients With Diffuse Large B-Cell Lymphoma Treated With Combination Chemotherapy With or Without Rituximab nanCOMPLETED
A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients nanCOMPLETED
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis nanCOMPLETED
Tecfidera Diffusion Tensor Imaging nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a EI24 binder may also engage these)

ProteinNameSimilarity
Q08DE5 1.000 Q08DE5 →
Q4KM77 1.000 Q4KM77 →
Q61070 1.000 Q61070 →
F1RAX4 0.987 F1RAX4 →
Q20123 0.984 Q20123 →
Q1MTR8 0.984 Q1MTR8 →
Q28FG4 0.984 Q28FG4 →
Q9UTD3 0.984 Q9UTD3 →
Q298S5 0.983 Q298S5 →
A2XX57 0.983 A2XX57 →
B4J2W3 0.983 B4J2W3 →
B4HEB1 0.983 B4HEB1 →
B4N5D3 0.983 B4N5D3 →
Q500V2 0.983 Q500V2 →
Q750Q7 0.982 Q750Q7 →
Q0V9G6 0.982 Q0V9G6 →
B0D4E6 0.982 B0D4E6 →
Q9UI14 0.982 Q9UI14 →
B4PF15 0.982 B4PF15 →
B3NGS7 0.982 B3NGS7 →
B4LC58 0.982 B4LC58 →
Q9HBG4 0.982 Q9HBG4 →
Q641M3 0.982 Q641M3 →
Q9LIC7 0.982 Q9LIC7 →
Q74ZS2 0.982 Q74ZS2 →
Q6GMB1 0.982 Q6GMB1 →
Q9P055 0.982 Q9P055 →
Q8BH47 0.982 Q8BH47 →
C4JDF8 0.981 C4JDF8 →
Q6DF80 0.981 Q6DF80 →