Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31712882 | 0.82 | RET (0.44) | NPC1RAB9ASMN1; SMN2HPGDSALDH1A1 | |
| SCHEMBL29875709 | 0.79 | LCK (0.35) | TSHR | |
| SCHEMBL29685367 | 0.70 | IP6K1 (0.43) | SMN1; SMN2HPGDS | |
| SCHEMBL29875412 | 0.68 | MAPK1 (0.38) | MEN1KMT2APARP1 | |
| SCHEMBL30333440 | 0.68 | CHRM2 (0.41) | CNR2MEN1KMT2AAPOBEC3GCHRM2 | |
| SCHEMBL24541013 | 0.68 | LCK (0.41) | NPC1RAB9ATSHRALDH1A1KDM4E | |
| SCHEMBL29685869 | 0.65 | IP6K1 (0.39) | TSHRSMN1; SMN2PARP1 | |
| SCHEMBL26918319 | 0.65 | IP6K1 (0.39) | TSHRSMN1; SMN2PARP1 | |
| SCHEMBL15631152 | 0.65 | CHRM2 (0.46) | MEN1KMT2AAPOBEC3GCHRM2GRM5 | |
| SCHEMBL31712899 | 0.64 | SIRT6 (0.37) | KMT2ANPC1RAB9ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251624-B1 | TRICYCLIC CARBOXAMIDE DERIVATIVES AS PRMT5 INHIBITORS | AMGEN INC (US) | 2025-10-29 | — | — | EP | claimed |