Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31716946 | 0.85 | LMNA (0.44) | KDM4ELMNAROCK2PDE10A | |
| SCHEMBL31717042 | 0.84 | LMNA (0.43) | KDM4ELMNAROCK2PDE10A | |
| SCHEMBL31716955 | 0.84 | LMNA (0.43) | KDM4ELMNAROCK2 | |
| SCHEMBL31716050 | 0.84 | LMNA (0.43) | KDM4ELMNAROCK2 | |
| SCHEMBL31716882 | 0.83 | MAPK1 (0.46) | KDM4ELMNAROCK2PDE10A | |
| SCHEMBL31715994 | 0.82 | KDM4E (0.46) | KDM4ELMNAROCK2 | |
| SCHEMBL31715980 | 0.82 | LMNA (0.42) | KDM4ELMNAROCK2PDE10A | |
| SCHEMBL31716099 | 0.80 | LMNA (0.41) | KDM4ELMNAROCK2PDE10A | |
| SCHEMBL31716260 | 0.79 | PDE5A (0.36) | KDM4ELMNAROCK2ROCK1TUBB4A | |
| SCHEMBL31716584 | 0.77 | KDM4E (0.60) | KDM4ELMNAHSD17B10ROCK2GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |