Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31720704 | 0.90 | MCOLN2 (0.57) | MCOLN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL31720691 | 0.90 | MCOLN2 (0.60) | MCOLN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL31720716 | 0.87 | MCOLN2 (0.56) | MCOLN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL31720766 | 0.85 | MCOLN2 (0.54) | MCOLN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL31720659 | 0.83 | MCOLN2 (0.58) | MCOLN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL30936649 | 0.80 | MCOLN2 (0.49) | MCOLN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL31720591 | 0.80 | MCOLN2 (0.49) | MCOLN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL31720611 | 0.79 | MCOLN2 (0.46) | MCOLN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL30936607 | 0.78 | MCOLN2 (0.60) | MCOLN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL31720615 | 0.78 | MCOLN2 (0.63) | MCOLN2TSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250340510-A1 | Substituted Phenylbenzenesulfonamide Derivatives and Uses Thereof | NINE SQUARE THERAPEUTICS CORPORATION (US) | 2025-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250340510-A1 | Substituted Phenylbenzenesulfonamide Derivatives and Uses Thereof | TRPM2, TRPM6, TRPM5 | MCOLN2 19/4885TSHR 4552/4885MEN1 2343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.