Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14075637 | 0.80 | LOXL2 (0.69) | LOXL2KDM4EHPGDHSD17B10AGXT | |
| SCHEMBL13195275 | 0.78 | LOXL2 (0.53) | LOXL2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL340071 | 0.76 | LOXL2 (0.47) | LOXL2NPC1RAB9AAGXTCYP19A1 | |
| SCHEMBL16429505 | 0.75 | CYP11B1 (0.63) | LOXL2NPC1AGXTCYP19A1MKNK1 | |
| SCHEMBL6427450 | 0.73 | TAAR1 (0.54) | LOXL2AGXTCYP19A1ADRA2ASMN1; SMN2 | |
| SCHEMBL7806512 | 0.73 | LOXL2 (0.60) | LOXL2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25059324 | 0.72 | LOXL2 (0.46) | LOXL2ALDH1A1AGXTCYP19A1ADRA2A | |
| SCHEMBL29067195 | 0.71 | RAB9A (0.44) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL29830938 | 0.71 | L3MBTL1 (0.59) | ALDH1A1SMN1; SMN2L3MBTL1ASIC3LMNA | |
| SCHEMBL41191 | 0.71 | L3MBTL1 (0.59) | ALDH1A1SMN1; SMN2L3MBTL1ASIC3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250339520-A1 | COMPOSITIONS AND METHODS FOR USE IN KRAS-TARGETED THERAPIES FOR THE TREATMENT OF CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-11-06 | — | — | US | claimed |
| US-20250339520-A1 | COMPOSITIONS AND METHODS FOR USE IN KRAS-TARGETED THERAPIES FOR THE TREATMENT OF CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-11-06 | — | — | US | disclosed |