Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL31722606 | 0.86 | HRH3 (0.45) | HRH3NPC1RAB9AKMT2AMAPT | |
| SCHEMBL31198943 | 0.85 | HRH3 (0.52) | HRH3MAPK1TGM2GPR119NPC1 | |
| SCHEMBL30680858 | 0.82 | HRH3 (0.58) | HRH3MAPK1TGM2GPR119MAPT | |
| SCHEMBL22629266 | 0.82 | HRH3 (0.58) | HRH3MAPK1NPC1RAB9AKMT2A | |
| SCHEMBL24421142 | 0.82 | HRH3 (0.58) | HRH3MAPK1TGM2GPR119MAPT | |
| SCHEMBL31752976 | 0.81 | HRH3 (0.57) | HRH3MAPK1TGM2GPR119NPC1 | |
| SCHEMBL7130127 | 0.80 | ALDH1A1 (0.57) | NPC1RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14875984 | 0.80 | HRH3 (0.57) | HRH3MAPK1NPC1RAB9AKMT2A | |
| SCHEMBL30723925 | 0.79 | CHRNB2 (0.53) | HRH3MAPT | |
| SCHEMBL64453 | 0.79 | HRH3 (0.54) | HRH3MAPK1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| WO-2025228947-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF INDUCING DEGRADATION OF POLO-LIKE KINASE1 | CROSSFIRE ONCOLOGY B.V. (NL) | 2025-11-06 | — | — | WO | disclosed |