Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393639 | 0.74 | HTT (0.33) | — | |
| SCHEMBL28321514 | 0.74 | ADORA1 (0.30) | — | |
| SCHEMBL27993571 | 0.72 | — | — | |
| SCHEMBL14049093 | 0.71 | TLR8 (0.33) | ALDH1A1CYP2C19 | |
| SCHEMBL11131428 | 0.71 | ALDH1A1 (0.37) | ALDH1A1CYP2C19 | |
| Water SCHEMBL8865234 | 0.70 | ALDH1A1 (0.33) | ALDH1A1CYP2C19 | |
| SCHEMBL11112327 | 0.70 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8724985 | 0.68 | ALDH1A1 (0.33) | ALDH1A1CYP2C19 | |
| SCHEMBL7291206 | 0.67 | LMNA (0.32) | ALDH1A1CYP2C19 | |
| SCHEMBL7274718 | 0.67 | LMNA (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912551-B | Recyclable aromatic amine reagent and preparation and application thereof | 浙江新和成股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115850112-A | Treatment method and application of 2-methyl-4-amino-5-formamidomethylpyrimidine synthetic mother liquor | 江苏兄弟维生素有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-113912551-A | Recyclable aromatic amine reagent and preparation and application thereof | 浙江新和成股份有限公司 | 2022-01-11 | — | — | CN | claimed |
| CN-110452181-B | Synthesis method of 2-methyl-4-amino-5-formamide methylpyrimidine | 厦门金达威维生素有限公司 | 2021-01-08 | — | — | CN | claimed |
| CN-109369540-B | Synthesis method of 2-methyl-4-amino-5-formamido methylpyrimidine | 浙江本立科技股份有限公司 | 2020-09-01 | — | — | CN | claimed |
| CN-110452181-A | The synthetic method of 2- methyl -4- amino -5- formamide methylpyrimidine | XIAMEN KINGDOMWAY VITAMIN CO LTD | 2019-11-15 | — | — | CN | claimed |
| US-3954756-A | Method for producing pyrimidine | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-05-04 | — | — | US | claimed |
| CN-119350183-A | Process for synthesizing enamine from 2-methyl-4-amino-5-formamidomethyl pyrimidine mother liquor and application thereof | 江苏兄弟维生素有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-113912551-B | Recyclable aromatic amine reagent and preparation and application thereof | 浙江新和成股份有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-113912551-B | Recyclable aromatic amine reagent and preparation and application thereof | 浙江新和成股份有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-115850112-A | Treatment method and application of 2-methyl-4-amino-5-formamidomethylpyrimidine synthetic mother liquor | 江苏兄弟维生素有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115850112-A | Treatment method and application of 2-methyl-4-amino-5-formamidomethylpyrimidine synthetic mother liquor | 江苏兄弟维生素有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-114163389-A | Preparation process of 2-methyl-4-amino-5-aminomethyl pyrimidine and methyl formate | 江苏兄弟维生素有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-110452181-A | The synthetic method of 2- methyl -4- amino -5- formamide methylpyrimidine | XIAMEN KINGDOMWAY VITAMIN CO LTD | 2019-11-15 | — | — | CN | disclosed |
| EP-2102172-B1 | SYNTHESIS OF 4-AMINO-PYRIMIDINES | DSM IP ASSETS BV (NL) | 2015-08-12 | — | — | EP | disclosed |
| US-8198443-B2 | Synthesis of 4-amino-pyrimidines scaffolds | DSM IP ASSETS B.V. (NL) | 2012-06-12 | — | — | US | disclosed |
| US-20100016591-A1 | SYNTHESIS OF 4-AMINO-PYRIMIDINES SCAFFOLDS | DSM IP ASSETS B.V. (NL) | 2010-01-21 | — | — | US | disclosed |
| EP-2102172-A1 | SYNTHESIS OF 4-AMINO-PYRIMIDINES | DSM IP Assets B.V. (NL) | 2009-09-23 | — | — | EP | disclosed |
| EP-1972620-A1 | Synthesis of 4-amino-pyrimidines | DSMIP Assets B.V. (NL) | 2008-09-24 | — | — | EP | disclosed |
| WO-2008087021-A1 | SYNTHESIS OF 4-AMINO-PYRIMIDINES | DSM IP ASSETS B.V. (NL) | 2008-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016591-A1 | SYNTHESIS OF 4-AMINO-PYRIMIDINES SCAFFOLDS | HRH3, HRH4, CBR3 | ALDH1A1 1902/4885CYP2C19 3641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.