Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321514 | 0.81 | ADORA1 (0.30) | HTTSMN1; SMN2LMNA | |
| SCHEMBL21353948 | 0.77 | HTT (0.35) | HTTSMN1; SMN2LMNA | |
| SCHEMBL3172280 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL21393637 | 0.74 | HEXA (0.32) | HTTSMN1; SMN2 | |
| SCHEMBL11131428 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL1830380 | 0.69 | LMNA (0.40) | HTTSMN1; SMN2LMNA | |
| SCHEMBL1396931 | 0.69 | LMNA (0.35) | HTTSMN1; SMN2LMNA | |
| SCHEMBL19478935 | 0.69 | NUDT1 (0.35) | — | |
| SCHEMBL11713959 | 0.67 | ALDH1A1 (0.33) | LMNA | |
| SCHEMBL23257898 | 0.67 | LMNA (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |