Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 2/20 | 0.45 |
| ▸ | EDNRB | P24530 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723073 | 0.90 | NPC1 (0.43) | CYP19A1ALDH1A1NAMPTCYP2C9KDM4E | |
| SCHEMBL24314215 | 0.90 | NPC1 (0.43) | CYP19A1ALDH1A1NAMPTCYP2C9KDM4E | |
| SCHEMBL31723102 | 0.85 | MEN1 (0.44) | ALDH1A1L3MBTL1KDM4EPOLBPTGER4 | |
| SCHEMBL24313949 | 0.85 | MEN1 (0.44) | ALDH1A1L3MBTL1KDM4EPOLBPTGER4 | |
| SCHEMBL30538408 | 0.82 | BCAT1 (0.55) | ALDH1A1KDM4ESMN1; SMN2TP53HPGD | |
| SCHEMBL24313562 | 0.81 | NPC1 (0.46) | ALDH1A1KDM4EPOLBSMN1; SMN2TDP1 | |
| SCHEMBL24313791 | 0.81 | KDM4E (0.51) | ALDH1A1KDM4EPOLBSMN1; SMN2PTGER4 | |
| SCHEMBL31723074 | 0.81 | KDM4E (0.51) | ALDH1A1KDM4EPOLBSMN1; SMN2PTGER4 | |
| SCHEMBL24313971 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4EPOLBSMN1; SMN2PTGER4 | |
| SCHEMBL24314219 | 0.79 | BCAT1 (0.42) | ALDH1A1KDM4EPOLBSMN1; SMN2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229045-B1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | BROAD INST INC (US) | 2025-11-12 | — | — | EP | claimed |