SCHEMBL31723189

SCHEMBL31723189

Cc1cc(N)c(Cl)c(Nc2cccc(C(C)C)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FADS1 O60427 1/20 0.42
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
IDO1 P14902 1/20 0.39
JAK2 O60674 1/20 0.37
RAPGEF4 Q8WZA2 1/20 0.37
KIF11 P52732 1/20 0.36
P2RX3 P56373 3/20 0.35
CA2 P00918 1/20 0.35
BRD4 O60885 1/20 0.35
KAT2B Q92831 1/20 0.35
BRD9 Q9H8M2 1/20 0.35
EGFR P00533 1/20 0.35
TNNI3K Q59H18 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22231922 1.00 FADS1 (0.42) FADS1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29454143 1.00 FADS1 (0.42) FADS1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29454112 0.84 NPSR1 (0.49) RAPGEF4CA2BRD4KAT2BBRD9
SCHEMBL31723203 0.82 FADS1 (0.46) FADS1RAPGEF4EGFRGAAMAPT
SCHEMBL29454046 0.82 FADS1 (0.46) FADS1RAPGEF4EGFRGAAMAPT
SCHEMBL22231908 0.82 FADS1 (0.46) FADS1RAPGEF4EGFRGAAMAPT
SCHEMBL22231911 0.81 GAA (0.50) BRD4KAT2BBRD9GAAMAPT
SCHEMBL29454250 0.81 GAA (0.50) BRD4KAT2BBRD9GAAMAPT
SCHEMBL31723231 0.80 RAPGEF4 (0.53) RAPGEF4EGFRKDR
SCHEMBL22231784 0.80 RAPGEF4 (0.53) RAPGEF4EGFRKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed