SCHEMBL31723193

SCHEMBL31723193

Cc1cc(N)c(Cl)c(N(C)c2ccccc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHKA P35790 6/20 0.39
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
MAPK13 O15264 1/20 0.36
MAPK12 P53778 1/20 0.36
MAPK11 Q15759 1/20 0.36
MAPK14 Q16539 1/20 0.36
CHKB Q9Y259 1/20 0.34
DHFR P00374 2/20 0.33
EGFR P00533 1/20 0.33
CSF1R P07333 1/20 0.33
HTT P42858 1/20 0.33
GAA P10253 1/20 0.33
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
MAPT P10636 2/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454202 1.00 CHKA (0.39) CHKAKMT2AMEN1MAPK13MAPK12
SCHEMBL31723186 0.87 CSF1R (0.37) KMT2AMEN1MAPK13MAPK12MAPK11
SCHEMBL29454133 0.87 CSF1R (0.37) KMT2AMEN1MAPK13MAPK12MAPK11
SCHEMBL22232301 0.87 CSF1R (0.37) KMT2AMEN1MAPK13MAPK12MAPK11
SCHEMBL29454089 0.87 GAA (0.40) CHKAKMT2AMAPK13MAPK12MAPK11
SCHEMBL31723223 0.87 GAA (0.40) CHKAKMT2AMAPK13MAPK12MAPK11
SCHEMBL22232145 0.86 HTR3E (0.43) CHKAKMT2AMEN1MAPK13MAPK12
SCHEMBL29454118 0.86 HTR3E (0.43) CHKAKMT2AMEN1MAPK13MAPK12
SCHEMBL31723251 0.86 HTR3E (0.43) CHKAKMT2AMEN1MAPK13MAPK12
SCHEMBL22232378 0.84 SLC6A2 (0.35) KMT2AMAPK13MAPK12MAPK11MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed