SCHEMBL31723223

SCHEMBL31723223

Cc1cc(N)c(Cl)c(N(C)c2ccc(Cl)cc2)c1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
CHKA P35790 10/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
CYP3A4 P08684 1/20 0.36
KCNH2 Q12809 1/20 0.35
SCN5A Q14524 1/20 0.35
SCN9A Q15858 1/20 0.35
APP P05067 1/20 0.34
MAPK13 O15264 1/20 0.34
MAPK12 P53778 1/20 0.34
MAPK11 Q15759 1/20 0.34
MAPK14 Q16539 1/20 0.34
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454089 1.00 GAA (0.40) GAAKMT2ACHKALMNAMAPT
SCHEMBL22232378 0.87 SLC6A2 (0.35) GAAKMT2AAPPMAPK13MAPK12
SCHEMBL29454090 0.87 SLC6A2 (0.35) GAAKMT2AAPPMAPK13MAPK12
SCHEMBL29454202 0.87 CHKA (0.39) GAAKMT2ACHKALMNAMAPT
SCHEMBL31723193 0.87 CHKA (0.39) GAAKMT2ACHKALMNAMAPT
SCHEMBL31723191 0.84 MAPK13 (0.34) GAAKMT2AMAPK13MAPK12MAPK11
SCHEMBL29454096 0.84 MAPK13 (0.34) GAAKMT2AMAPK13MAPK12MAPK11
SCHEMBL22232065 0.84 TUBB4A (0.38) CYP3A4
SCHEMBL29454087 0.84 TUBB4A (0.38) CYP3A4
SCHEMBL22232145 0.83 HTR3E (0.43) GAAKMT2ACHKAMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed