SCHEMBL31723186

SCHEMBL31723186

Cc1cccc(N(C)c2cc(C)cc(N)c2Cl)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 5/20 0.37
SIGMAR1 Q99720 2/20 0.37
EGFR P00533 4/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
MAPK13 O15264 1/20 0.35
MAPK12 P53778 1/20 0.35
MAPK11 Q15759 1/20 0.35
MAPK14 Q16539 1/20 0.35
TSHR P16473 1/20 0.35
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34
LMNA P02545 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
POLB P06746 1/20 0.34
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
THRB P10828 1/20 0.33
ALOX15 P16050 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454133 1.00 CSF1R (0.37) CSF1RSIGMAR1EGFRSMN1; SMN2MAPK13
SCHEMBL22232301 1.00 CSF1R (0.37) CSF1RSIGMAR1EGFRSMN1; SMN2MAPK13
SCHEMBL22232145 0.89 HTR3E (0.43) CSF1REGFRMAPK13MAPK12MAPK11
SCHEMBL31723251 0.89 HTR3E (0.43) CSF1REGFRMAPK13MAPK12MAPK11
SCHEMBL29454118 0.89 HTR3E (0.43) CSF1REGFRMAPK13MAPK12MAPK11
SCHEMBL29454202 0.87 CHKA (0.39) CSF1REGFRMAPK13MAPK12MAPK11
SCHEMBL31723193 0.87 CHKA (0.39) CSF1REGFRMAPK13MAPK12MAPK11
SCHEMBL22231968 0.87 ACHE (0.37) MAPK13MAPK12MAPK11MAPK14ACHE
SCHEMBL31723215 0.87 ACHE (0.37) MAPK13MAPK12MAPK11MAPK14ACHE
SCHEMBL29454065 0.87 ACHE (0.37) MAPK13MAPK12MAPK11MAPK14ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed