Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29454179 | 1.00 | RAPGEF4 (0.58) | RAPGEF4CYP3A4GAAMAPTKDM4E | |
| SCHEMBL22231877 | 1.00 | RAPGEF4 (0.58) | RAPGEF4CYP3A4GAAMAPTKDM4E | |
| SCHEMBL29454122 | 0.82 | MAPK14 (0.40) | RAPGEF4GAAMAPTALDH1A1TDP1 | |
| SCHEMBL22231766 | 0.82 | MAPK14 (0.40) | RAPGEF4GAAMAPTALDH1A1TDP1 | |
| SCHEMBL22231933 | 0.81 | NUDT1 (0.40) | RAPGEF4CYP3A4MAPTTDP1APP | |
| SCHEMBL31723200 | 0.81 | NUDT1 (0.40) | RAPGEF4CYP3A4MAPTTDP1APP | |
| SCHEMBL29454149 | 0.81 | NUDT1 (0.40) | RAPGEF4CYP3A4MAPTTDP1APP | |
| SCHEMBL22232474 | 0.80 | NPC1 (0.44) | RAPGEF4CYP3A4GAAMAPTKDM4E | |
| SCHEMBL29454186 | 0.80 | NPC1 (0.44) | RAPGEF4CYP3A4GAAMAPTKDM4E | |
| SCHEMBL31723255 | 0.77 | RAPGEF4 (0.44) | RAPGEF4CYP3A4KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647426-A2 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | PI Industries Ltd. (IN) | 2025-11-12 | — | — | EP | claimed |