SCHEMBL29454149

SCHEMBL29454149

Cc1cc(N)c(Cl)c(Nc2ccc(Cl)cc2F)c1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
KMT2A Q03164 2/20 0.39
KDR P35968 5/20 0.38
EGFR P00533 3/20 0.38
APP P05067 1/20 0.38
RAPGEF4 Q8WZA2 2/20 0.37
FLT1 P17948 4/20 0.37
FGFR1 P11362 2/20 0.37
EPHB2 P29323 1/20 0.37
FLT4 P35916 1/20 0.37
CYP3A4 P08684 1/20 0.37
TRPM5 Q9NZQ8 1/20 0.35
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAP2K1 Q02750 1/20 0.35
PDGFRB P09619 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22231933 1.00 NUDT1 (0.40) NUDT1NPSR1KMT2AKDREGFR
SCHEMBL31723200 1.00 NUDT1 (0.40) NUDT1NPSR1KMT2AKDREGFR
SCHEMBL22231787 0.88 SOS1 (0.39) KMT2AMAPTTDP1
SCHEMBL31723198 0.88 SOS1 (0.39) KMT2AMAPTTDP1
SCHEMBL29454228 0.88 SOS1 (0.39) KMT2AMAPTTDP1
SCHEMBL31723243 0.83 SLC6A4 (0.38) KMT2AMAPTTDP1
SCHEMBL22232061 0.83 SLC6A4 (0.38) KMT2AMAPTTDP1
SCHEMBL29454105 0.83 SLC6A4 (0.38) KMT2AMAPTTDP1
SCHEMBL22231877 0.81 RAPGEF4 (0.58) APPRAPGEF4CYP3A4MAPTTDP1
SCHEMBL31723199 0.81 RAPGEF4 (0.58) APPRAPGEF4CYP3A4MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US claimed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US claimed
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof PI INDUSTRIES LTD. (IN) 2026-02-10 US disclosed
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP disclosed
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089523-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF H1-3, PRMT7, PFAS NUDT1 1434/4885NPSR1 1484/4885KMT2A 438/4885
US-12545639-B2 3-substituted phenylamidine compounds, preparation and use thereof CBR1, CBR3, HCCS NUDT1 2514/4885NPSR1 762/4885KMT2A 3264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.