SCHEMBL31723229

SCHEMBL31723229

Cc1c(N)cc(Cl)cc1Nc1cccc(F)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.45
EGFR P00533 2/20 0.41
STK10 O94804 1/20 0.41
SLK Q9H2G2 1/20 0.41
ABL1 P00519 1/20 0.41
ABL2 P42684 1/20 0.41
P2RY4 P51582 2/20 0.40
MEN1 O00255 2/20 0.40
RAB9A P51151 2/20 0.40
KMT2A Q03164 2/20 0.40
GRIK1 P39086 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
KDR P35968 2/20 0.38
TAAR1 Q96RJ0 2/20 0.38
DEPTOR Q8TB45 1/20 0.38
ABCG2 Q9UNQ0 2/20 0.37
FADS1 O60427 1/20 0.37
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454206 1.00 RAPGEF4 (0.45) RAPGEF4EGFRSTK10SLKABL1
SCHEMBL22232072 1.00 RAPGEF4 (0.45) RAPGEF4EGFRSTK10SLKABL1
SCHEMBL31723264 0.86 RAPGEF4 (0.49) RAPGEF4EGFRABL1ABL2P2RY4
SCHEMBL22232047 0.86 RAPGEF4 (0.49) RAPGEF4EGFRABL1ABL2P2RY4
SCHEMBL29454098 0.86 RAPGEF4 (0.49) RAPGEF4EGFRABL1ABL2P2RY4
SCHEMBL22231930 0.86 FADS1 (0.47) EGFRABL1ABL2P2RY4MEN1
SCHEMBL31723253 0.86 FADS1 (0.47) EGFRABL1ABL2P2RY4MEN1
SCHEMBL29454190 0.86 FADS1 (0.47) EGFRABL1ABL2P2RY4MEN1
SCHEMBL29454080 0.85 NPSR1 (0.47) EGFRABL1ABL2P2RY4RAB9A
SCHEMBL22232365 0.83 GAA (0.50) EGFRMEN1KMT2AKDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed