Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 3/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.48 |
| ▸ | TNF | P01375 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30224160 | 0.80 | PSMB1 (0.49) | PSMB1PSMB5KDM4EHTR7POLB | |
| SCHEMBL2950988 | 0.80 | PSMB1 (0.49) | PSMB1PSMB5KDM4EHTR7POLB | |
| SCHEMBL31241139 | 0.78 | PSMB1 (0.55) | PSMB1PSMB5TNFKDM4EPOLB | |
| SCHEMBL31559241 | 0.78 | PSMB1 (0.50) | PSMB1PSMB5TNFKDM4EPOLB | |
| SCHEMBL114949 | 0.77 | CYP2C9 (0.35) | HTR7 | |
| SCHEMBL18955878 | 0.76 | PSMB1 (0.58) | PSMB1PSMB5TNFKDM4EMCL1 | |
| SCHEMBL31723379 | 0.76 | MCL1 (0.56) | TNFPOLBMCL1DDR1LMNA | |
| SCHEMBL31240999 | 0.76 | PSMB1 (0.53) | PSMB1PSMB5TNF | |
| SCHEMBL20786907 | 0.74 | HTR7 (0.42) | PSMB1PSMB5TNFKDM4EHTR7 | |
| SCHEMBL31723380 | 0.74 | GRM2 (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |