Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 4/20 | 0.45 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24542521 | 0.81 | USP7 (0.49) | USP7HCAR1FPR2BACE1KDM4E | |
| SCHEMBL31548396 | 0.78 | USP7 (0.50) | USP7HCAR1BACE1KDM4EPKM | |
| SCHEMBL23531623 | 0.77 | USP7 (0.46) | USP7FPR2BACE1KDM4EPKM | |
| SCHEMBL31723351 | 0.77 | HSD17B13 (0.42) | KDM4EHSD17B13CDK9 | |
| SCHEMBL4768843 | 0.75 | KDM4E (0.51) | USP7BACE1KDM4EPKMGPR119 | |
| SCHEMBL12984965 | 0.74 | CDK9 (0.43) | USP7HCAR1FPR2BACE1KDM4E | |
| SCHEMBL31637366 | 0.74 | FAAH (0.42) | USP7HCAR1BACE1KDM4EPKM | |
| SCHEMBL23531649 | 0.74 | KDM4E (0.49) | USP7FPR2BACE1KDM4EPKM | |
| SCHEMBL3526294 | 0.73 | USP7 (0.51) | USP7FPR2BACE1KDM4EPKM | |
| SCHEMBL24753491 | 0.73 | HCAR1 (0.41) | HCAR1BACE1NPBWR1MCHR1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024147703-A1 | SHP2 INHIBITOR AND USES THEREOF | 주식회사 카나프테라퓨틱스 | 2024-07-11 | — | — | WO | disclosed |