Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727394 | 0.87 | DDB1 (0.42) | CRBNDDB1 | |
| SCHEMBL31134557 | 0.79 | DDB1 (0.50) | MAPTCRBNDDB1 | |
| Trifluoroacetic Acid SCHEMBL31727208 | 0.78 | CRBN (0.37) | ALDH1A1CRBNDDB1IKZF3BTK | |
| SCHEMBL31727238 | 0.76 | CRBN (0.41) | CRBNDDB1IKZF3BTK | |
| SCHEMBL31134471 | 0.75 | DDB1 (0.47) | ALDH1A1CRBNDDB1CHRM2IKZF3 | |
| SCHEMBL31727389 | 0.74 | MAPT (0.40) | MAPTSMN1; SMN2CRBNDDB1IKZF3 | |
| SCHEMBL30066511 | 0.71 | CRBN (0.54) | ALDH1A1CRBNDDB1CHRM2IKZF3 | |
| SCHEMBL31342208 | 0.70 | CRBN (0.40) | CRBNDDB1IKZF3 | |
| SCHEMBL31134634 | 0.69 | HTR6 (0.45) | CRBNDDB1 | |
| SCHEMBL31342558 | 0.69 | IKZF2 (0.40) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235363-A1 | CYCLIN-DEPENDENT KINASE 4 DEGRADERS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-11-13 | — | — | WO | disclosed |