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Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL31727208

Cc1nn(C2CCC(=O)NC2=O)c2cccc(N3CCN(C4CNC4)CC3)c12.O=C(O)C(F)(F)F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 16/20 0.37
▸ DDB1 Q16531 13/20 0.37
▸ KHK P50053 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ IKZF3 Q9UKT9 2/20 0.33
▸ TNF P01375 1/20 0.33
▸ IL1B P01584 1/20 0.33
▸ IKZF2 Q9UKS7 1/20 0.32
▸ BTK Q06187 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31727394 0.82 DDB1 (0.42) CRBNDDB1
SCHEMBL31134471 0.81 DDB1 (0.47) CRBNDDB1ALDH1A1IKZF3TNF
Trifluoroacetic Acid SCHEMBL26101941 0.80 CRBN (0.48) CRBNDDB1KDM4EALDH1A1IKZF2
SCHEMBL31134557 0.80 DDB1 (0.50) CRBNDDB1
SCHEMBL31726950 0.78 ALDH1A1 (0.34) CRBNDDB1ALDH1A1IKZF3BTK
SCHEMBL31727238 0.77 CRBN (0.41) CRBNDDB1IKZF3TNFIL1B
SCHEMBL31727389 0.75 MAPT (0.40) CRBNDDB1IKZF3BTK
SCHEMBL31134634 0.75 HTR6 (0.45) CRBNDDB1
SCHEMBL31342208 0.74 CRBN (0.40) CRBNDDB1IKZF3TNFIL1B
Trifluoroacetic Acid SCHEMBL29079580 0.74 DDB1 (0.37) CRBNDDB1IKZF3TNFIL1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235363-A1 CYCLIN-DEPENDENT KINASE 4 DEGRADERS BLUEPRINT MEDICINES CORPORATION (US) 2025-11-13 — — WO disclosed
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