Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15210675 | 0.81 | KDM4E (0.39) | KDM4EGLAMAPTPGRPOLB | |
| SCHEMBL3378382 | 0.76 | CYP3A4 (0.36) | KDM4EMAPTPGR | |
| SCHEMBL30788045 | 0.72 | PGR (0.49) | KDM4EGLAMAPTPGRPOLB | |
| SCHEMBL78315 | 0.72 | PGR (0.49) | KDM4EGLAMAPTPGRPOLB | |
| SCHEMBL31349150 | 0.69 | SMN1; SMN2 (0.37) | KDM4EGLAMAPTPOLB | |
| SCHEMBL7847441 | 0.69 | PTGDR2 (0.40) | — | |
| Hydrochloric Acid SCHEMBL31283718 | 0.68 | SMN1; SMN2 (0.36) | KDM4EGLAMAPTPOLB | |
| SCHEMBL4472584 | 0.67 | RAB9A (0.38) | MAPTPOLBAAK1 | |
| SCHEMBL29427131 | 0.67 | KDM1A (0.46) | KDM4EGLAMAPTPOLB | |
| SCHEMBL3714362 | 0.67 | KDM1A (0.46) | KDM4EGLAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235363-A1 | CYCLIN-DEPENDENT KINASE 4 DEGRADERS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-11-13 | — | — | WO | disclosed |