Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 7/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727317 | 0.82 | CUL4A (0.45) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL31727714 | 0.81 | CHRNB2 (0.40) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL31728273 | 0.79 | OPRK1 (0.37) | CHRNB4CHRNA3OPRK1 | |
| SCHEMBL31728001 | 0.78 | NPC1 (0.31) | CHRNB4CHRNA3MAPT | |
| SCHEMBL31727057 | 0.74 | GPR119 (0.39) | TIPARPOPRK1 | |
| SCHEMBL31727588 | 0.73 | MAPT (0.36) | MAPTOPRK1 | |
| SCHEMBL31728267 | 0.71 | OPRK1 (0.34) | MAPTOPRK1 | |
| SCHEMBL31727915 | 0.70 | HRH4 (0.31) | OPRK1 | |
| SCHEMBL30730434 | 0.69 | KCNH2 (0.45) | CYP1A2CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL27173031 | 0.69 | KCNH2 (0.45) | CYP1A2CYP3A4MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025231561-A1 | TERTIARY AMINE-SUBSTITUTED BIPYRIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND THEIR USE AS PHARMACEUTICALS | UNIVERSITE DE MONTREAL (CA) | 2025-11-13 | — | — | WO | disclosed |