Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791587 | 0.76 | MAPT (0.39) | MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL30773532 | 0.75 | MAPT (0.63) | MAPTNPC1KMT2ARAB9AALDH1A1 | |
| SCHEMBL28384656 | 0.75 | MAPT (0.63) | MAPTNPC1KMT2ARAB9AALDH1A1 | |
| SCHEMBL19302284 | 0.75 | PYCR1 (0.53) | MAPTKMT2AALDH1A1LMNAPARP1 | |
| SCHEMBL6741043 | 0.74 | MAPT (0.49) | MAPTNPC1KMT2ARAB9AALDH1A1 | |
| SCHEMBL10265072 | 0.74 | MAPT (0.42) | MAPTNPC1KMT2ARAB9AALDH1A1 | |
| SCHEMBL4525335 | 0.72 | ALDH1A1 (0.49) | MAPTRAB9AALDH1A1POLBHTT | |
| SCHEMBL1099100 | 0.72 | RAB9A (0.45) | MAPTNPC1KMT2ARAB9AALDH1A1 | |
| SCHEMBL21640132 | 0.72 | MAPT (0.36) | MAPTRAB9AALDH1A1LMNAPOLB | |
| SCHEMBL2144585 | 0.71 | CYP19A1 (0.47) | MAPTCRHBPCRHR2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235363-A1 | CYCLIN-DEPENDENT KINASE 4 DEGRADERS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-11-13 | — | — | WO | disclosed |