Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728886 | 0.86 | KDR (0.34) | EIF2AK3 | |
| SCHEMBL31728385 | 0.83 | PIK3CD (0.35) | — | |
| SCHEMBL31728352 | 0.82 | PIK3CD (0.34) | EIF2AK3 | |
| SCHEMBL31728482 | 0.82 | — | — | |
| SCHEMBL31728594 | 0.82 | SRC (0.35) | EIF2AK3 | |
| SCHEMBL31728414 | 0.81 | — | — | |
| SCHEMBL31728546 | 0.81 | — | — | |
| SCHEMBL31728557 | 0.81 | RPS6KA1 (0.31) | — | |
| SCHEMBL31728043 | 0.80 | LRRK2 (0.31) | HTR1ADRD2HTR7HTR6 | |
| SCHEMBL31728213 | 0.79 | EIF2AK3 (0.38) | EIF2AK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |