Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | HCK | P08631 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.35 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728482 | 0.84 | — | — | |
| SCHEMBL31727822 | 0.82 | EIF2AK3 (0.31) | EIF2AK3 | |
| SCHEMBL31728557 | 0.82 | RPS6KA1 (0.31) | — | |
| SCHEMBL31727802 | 0.75 | SRC (0.34) | SRCEGFRPIK3CDABL1HCK | |
| SCHEMBL31728043 | 0.72 | LRRK2 (0.31) | SRCEGFRPIK3CDABL1HCK | |
| SCHEMBL31728572 | 0.69 | — | — | |
| SCHEMBL31728886 | 0.69 | KDR (0.34) | SRCEGFRPIK3CDABL1HCK | |
| SCHEMBL31728454 | 0.69 | EIF2AK3 (0.36) | EGFRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL31727943 | 0.67 | PIK3CD (0.35) | SRCEGFRPIK3CDABL1HCK | |
| SCHEMBL31728767 | 0.67 | PIK3CD (0.41) | SRCEGFRPIK3CDABL1HCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |